B12 deficiency and pernicious anaemia - Leukemia and the house officer (links 31-58)

Web-based references relating to the number under the disk sign, listed by page header


B12 deficiency and pernicious anaemia
31 No link available; page 321

An approach to haemolytic anaemia
No links

Causes of haemolytic anaemia
32 D Weatherall & A Provan 2000 Lancet 355 1169; page 324

33 Professor Christine Lawrence [Link]; page 325

34 Professor Barbara Bain [Link]; page 325

35 Professor Barbara Bain [Link]; page 325

36 Professor Barbara Bain [Link]; page 325

37 Professor Barbara Bain [Link]; page 325

38 Professor Barbara Bain [Link]; page 325

39 Professor Barbara Bain [Link]; page 325

Sickle-cell anaemia
40 Adams RJ, McKie VC, Hsu L, et al. Prevention of a first stroke by transfusions in children with sickle cell anemia and abnormal results on transcranial Doppler ultrasonography. N Engl J Med 1998; 339:5-11. [Link]; page 326

41 PS Bellett 1996 e-bm 1 76; page 326

42 J Williams nejm 1993 329 472+501; page 326

(footnote) Charache S, Terrin ML, Moore RD, et al. Effect of hydroxyurea on frequency of painful crises in sickle cell anemia. N Engl J Med 1995; 332: 1317-1322. [Link]; page 326

(footnote) Steinberg MH, Barton F, Castro O, et al. Effect of hydroxyurea on mortality and morbidity in adult sickle cell anemia. JAMA 2003; 289: 1645-1651. [Link]; page 326

43 Vichinsky EP, Neumayr LD, Earles AN et al.; page N Engl J Med; 2000 Jun 22 ; 342(25):1855-65. PubMed ID: 10861320.

[Link] ; page 327

44 Vichinsky EP, Neumayr LD, Earles AN, et al. Causes and outcomes of the acute chest syndrome in sickle cell disease. N Engl J Med 2000; 342: 1855-1865. [Link]; page 327

45; page Gill 1998 bmj 317 761; page 327

46 Professor Christine Lawrence [Link]; page 327

47 Professor Christine Lawrence [Link]; page 327

Thalassaemia
(footnote) [Link]; page 327

48 Rund D, Rachmilewitz E.Beta-thalassemia.N Engl J Med 2005 ; 353(11): 1135-46.; [Link]; page 328

50 One genetic cause of thrombocytopenia is autoimmune lymphoproliferative syndrome (alps) with splenomegaly, lymphadenopathy + other autoimmune features, mentioned here because of its interesting pathogenesis related to faulty apoptosis (programmed cell death of lymphocytes activated via routine infections) due to mutation of the gene known as Fas'. Apoptosis is essential immunological function, and is regulated by the Fas/Apo-1 receptor (Blood 1997 89 1341).; page 328

51 Dr. Erwin van den Enden [Link]; page 329

52 Image of skull x ray in Thalassaemia Major; courtesy of the crookston collection [Link]; page 329

Bleeding disorders
53 (NB this was mistakenly numbered "49" in the book); page Image of haematoma in leg -- mild haemophilia -- after an IM injection;; page [Link] ; page 331

An approach to bleeding
No links

Anticoagulants
54 No link available; page 334

55 No link available; page 335

56 No link available; page 335

Leukemia and the house officer
57 Bernard GR, Vincent JL, Laterre PF, et al. Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med. 2001; 344: 699-709. [Link]; page 336

58 Image of DIC/purpura fulminans courtesy of the Crookston Collection [Link]; page 337

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