Chapter 01: Obstetrics

Web-based references relating to the number under the disk sign

1 SDMS CME on The Umbilicus [Link]; page 0

2 Intimate partner violence: causes and prevention. Author: Jewkes R. Journal: Lancet; 2002 Apr 20 ; 359(9315):1423-9. PubMed ID: 11978358. [Link]; page 1

3 EBM 1997 2 150; no link available; page 1

4 Office for National statistics 2007. England & Wales [Link]; page 1

5 Effect of the interval between pregnancies on perinatal outcomes. Zhu BP, N Engl J Med; 1999 Feb 25 ; 340(8):589-94. PubMed ID: 10029642 [Link]; page 2

6 A Andersen 2000 BMJ 320 1708 [Link]; page 2

7 he use of a birthroom: a randomized controlled trial comparing delivery with that in the labour ward. Author: Chapman MG, Jones M, Spring JE, De Swiet M, Chamberlain GV. Journal: Br J Obstet Gynaecol; 1986 Feb ; 93(2):182-7. PubMed ID: 3511958. [Link]; page 4

8 Birth Centre (Ashurst, UK) [Link]; page 4

9 BMJ. 1998 Feb 21;316(7131):566-7. Macfarlane A. At last--maternity statistics for England. [Link]; page 5

10 Pregnancy weight gain and postpartum loss: avoiding obesity while optimizing the growth and development of the fetus. Author: Lederman SA. Journal: J Am Med Womens Assoc; 2001 Spring ; 56(2):53-8. PubMed ID: 11326797. [Link]; page 7

11 High prevalence of vitamin D deficiency in pregnant non-Western women in The Hague, Netherlands. Author: van der Meer IM, Karamali NS, Boeke AJ, Lips P, Middelkoop BJ, Verhoeven I, Wuister JD. Journal: Am J Clin Nutr; 2006 Aug ; 84(2):350-3; quiz 468-9. PubMed ID: 16895882. [Link]; page 8

12 RCOG 2005 Greentop Guideline no 8 Amniocentesis and chorionic villus sampling [Link]; page 10

13 The value of sonography in early pregnancy for the detection of fetal abnormalities in an unselected population. Br J Obstet Gynaecol; 1999 Sep ; 106(9):929-36. PubMed ID: 10492104 [Link]; page 11

14 BMJ 1999;318:70-71 Down's syndrome, cardiac anomalies, and nuchal translucency Fetal heart failure might link nuchal translucency and Down's syndrome [Link]; page 11

15 Using fetal nuchal translucency to screen for major congenital cardiac defects at 10-14 weeks of gestation: population based cohort study. BMJ; 1999 Jan 9 ; 318(7176):81-5. PubMed ID: 9880278 [Link]; page 11

16 Screening performance of first-trimester nuchal translucency for major cardiac defects: a meta-analysis Makrydimas G, Am J Obstet Gynecol; 2003; 189:1330 PubMed ID: 14634564 [Link]; page 11

17 Fetal cardiac defects and increased nuchal translucency thickness: a prospective study. McAuliffe FM Am J Obstet Gynecol; 2004; 191:1486 PubMed ID: 15507988 [Link]; page 11

18 The clinical evaluation and pregnancy outcome of euploid fetuses with increased nuchal translucency. Maymon R Clin Genet; 2004; 66:426. PubMed ID: 15479188 [Link]; page 11

19 Chromosomal abnormality rates at amniocentesis and in live-born infants. Author: Hook EB, Cross PK, Schreinemachers DM. Journal: JAMA; 1983 Apr 15 ; 249(15):2034-8. PubMed ID: 6220164. [Link]; page 12

20 Down's syndrome screening is unethical: views of today's research ethics committees. Author: Reynolds TM. Journal: J Clin Pathol; 2003 Apr ; 56(4):268-70. PubMed ID: 12663637. [Link]; page 12

21 Risk factors for procedure-related fetal losses after mid-trimester genetic amniocentesis. Author: Kong CW, Leung TN, Leung TY, Chan LW, Sahota DS, Fung TY, Lau TK. Journal: Prenat Diagn; 2006 Oct ; 26(10):925-30. PubMed ID: 16838383. [Link]; page 12

22 RCOG Clinical Guideline 27 2005 Placenta praevia: diagnosis and management [Link]; page 14

23 Rudolph Cardinal 1998. Fetal development, placenta and maternal physiology. [Link]; page 15

24 Pre-eclampsia is associated with the failure of melanoma cell adhesion molecule (MCAM/CD146) expression by intermediate trophoblast. Qin Liu1. [Link]; page 15

25 RCOG 2004 Clinical Guideline 37 Thromboprophylaxis [Link]; page 16

26 Recurrence risk in hyperemesis gravidarum. Author: Trogstad LI, Stoltenberg C, Magnus P, Skjaerven R, Irgens LM. Journal: BJOG; 2005 Dec ; 112(12):1641-5. PubMed ID: 16305568. [Link]; page 18

27 Nasogastric enteral feeding in the management of hyperemesis gravidarum. Hsu JJ, Obstet Gynecol; 1996 Sep ; 88(3):343-6. PubMed ID: 8752236 [Link]; page 18

28 Percutaneous endoscopic gastrostomy with a jejunal port for severe hyperemesis gravidarum. Irving PM, Eur J Gastroenterol Hepatol; 2004; 16: 937. PubMed ID: 15316422 [Link]; page 18

29 BJOG. 2000 Feb;107(2):245-53. Sadler L. Pregnancy outcomes and cardiac complications in women with mechanical, bioprosthetic and homograft valves. [Link]; page 20

30 1. Selective serotonin reuptake inhibitors in pregnant women and neonatal withdrawal syndrome: a database analysis. Sanz E, Lancet; 2005 365 482. PubMed ID: 15705457 [Link]; page 21

31 BJOG. 2000 Apr;107(4):437-8. Guidotti RJ. Anaemia in pregnancy in developing countries. [Link]; page 22

32 [The effectiveness of three regimens using ferrous sulfate to treat anemia in pregnant women] Author: de Souza AI, Batista Filho M, Ferreira LO, Figueirôa JN. Journal: Rev Panam Salud Publica; 2004 May ; 15(5):313-9. PubMed ID: 15231078. [Link]; page 22

33 Duration of ruptured membranes and vertical transmission of HIV-1: a meta-analysis from 15 prospective cohort studies.Author: International Perinatal HIV Group .Journal: AIDS; 2001 Feb 16 ; 15(3):357-68. PubMed ID: 11273216. [Link]; page 23

34 Effect of breastfeeding and formula feeding on transmission of HIV-1: a randomized clinical trial. Nduati R, JAMA; 2000 Mar 1 ; 283(9):1167-74. PubMed ID: 10703779 [Link]; page 23

35 L Kuhn 2008. Effects of early, abrupt weaning on HIV-free Survival of Children in Zambia. NEJM 359 130 [Link]; page 23

36 RCOG Clinical Guideline 39 2004 Management of HIV in pregnancy [Link]; page 23

37 Paediatr Perinat Epidemiol. 1999 Oct;13(4):452-65. Williams MA. A population-based cohort study of the relation between maternal birthweight and risk of gestational diabetes mellitus in four racial/ethnic groups. [Link]; page 24

38 Diabetes. 1985 Jun;34 Suppl 2:106-10. Stowers JM. Long-range implications for the mother. The Aberdeen experience. [Link]; page 24

39 Dr François Nosten; Shoklo Malaria Research Unit (SMRU) is a field station attached to the Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand and is part of the Wellcome-Oxford-Mahidol-University-Research Programme. [Link]; page 27

40 Safety, efficacy and determinants of effectiveness of antimalarial drugs during pregnancy: implications for prevention programmes in Plasmodium falciparum-endemic sub-Saharan Africa. Author: Newman RD, Parise ME, Slutsker L, Nahlen B, Steketee RW. Journal: Trop Med Int Health; 2003 Jun ; 8(6):488-506. PubMed ID: 12791054 [Link]; page 27

41 ntermittent Presumptive Treatment for Malaria A better understanding of the pharmacodynamics will guide more rational policymaking--Nicholas J White [Link]; page 27

42 The longer term outcome of children born to mothers with epilepsy. Adab N, J Neurol Neurosurg Psychiatry; 2004; 75:1575 PubMed ID: 15491979 [Link]; page 29

43 [Link]; page 29

44 Thromboembolic Disease in Pregnancy and the Puerperium: Acute Management (28) - Apr 2001 [Link]; page 32

45 RCOG Clinical guidelines 28 2001 Thromboembolic disease in pregnancy and puerperium [Link]; page 32

46 I Greer 2000 NEJM 342 424 [Link]; page 33

47 British Heart Foundation Factfile 02/2002 [Link]; page 33

48 BJOG. 2000 Jan;107(1):84-8. Antsaklis AJ. Prenatal diagnosis of fetal primary cytomegalovirus infection. [Link]; page 34

49 AidsMap 2008 [Link]; page 34

50 Zidovudine with nevirapine for the prevention of HIV mother-to-child transmission reduces nevirapine resistance in mothers from the Western Cape, South Africa. Author: van Zyl GU, Claassen M, Engelbrecht S, Laten JD, Cotton MF, Theron GB, Preiser W. Journal: J Med Virol; 2008 Jun ; 80(6):942-6. PubMed ID: 18428139. [Link]; page 35

51 Guideline for preventing neonatal HIV. 2008 [Link]; page 35

52 K Kumwenda 2008. Extended antiviral prophylaxis to reduce breast-milk HIV-1 transmission. NEJM 359 119. [Link]; page 35

53 Tanania regimen for HIV in labour [Link]; page 35

54 Feasibility of prevention of perinatal HIV infection by nevirapine in rural areas of the northeast Democratic Republic of Congo, 2002-2004. Author: Kirere Mathe M, Sondag-Thull D, Lepage P. Journal: J Med Virol; 2008 May ; 80(5):772-6. PubMed ID: 18360889 [Link]; page 35

55 From PMTCT to a more comprehensive AIDS response for women: a much-needed shift. Author: Eyakuze C, Jones DA, Starrs AM, Sorkin N. Journal: Dev World Bioeth; 2008 Apr ; 8(1):33-42. PubMed ID: 18315723 [Link]; page 35

56 Br J Obstet Gynaecol. 1999 Jan;106(1):66-71. Newell ML. Antenatal screening for hepatitis B infection and syphilis in the UK. [Link]; page 36

57 N Engl J Med. 1999 Mar 11;340(10):798-9. Ince N. The increasing incidence of hepatocellular carcinoma. [Link]; page 36

58 Liver disease during pregnancy: acute viral hepatitis. Sookoian S. Ann Hepatol; 2006; 5:231. PubMed ID: 17060891 [Link]; page 36

59 Invest Ophthalmol Vis Sci. 2000 Dec;41(13):4074-9. Bowman RJ. Operational comparison of single-dose azithromycin and topical tetracycline for trachoma. [Link]; page 36

60 Selective neonatal BCG vaccination. Bakshi D, Acta Paediatr; 2004; 93:1207 PubMed ID: 15384885 [Link]; page 37

61 Appendicitis in pregnancy: new information that contradicts long-held clinical beliefs. Am J Obstet Gynecol; 2000 May ; 182(5):1027-9. PubMed ID: 10819817 [Link]; page 38

62 J Clin Ultrasound. 2001 Jun;29(5):306-11. Humphrey R. Rectus sheath hematoma in pregnancy. [Link]; page 38

63 Am J Perinatol. 1997 Jul;14(6):321-3. Ramirez MM. Spontaneous rectus sheath hematoma during pregnancy mimicking abruptio placenta. [Link]; page 38

64 The acute abdomen and the obstetrician. Baillieres Best Pract Res Clin Obstet Gynaecol; 2000 Feb ; 14(1):89-102. PubMed ID: 10789262 [Link]; page 38

65 Image of fetal positions drawn by OUP for OHCS-1 ; no link available; page 41

66 Hunter, William (1718-1783). Title: Anatomia uteri humani gravidi tabulis illustrata = The anatomy of the human gravid uterus exhibited in figures. [Link]; page 41

67 Image of pelvic diametres vs fetal head drawn by OUP for OHCS-2 ; no link available; page 43

68 Image of fetal heart rate patterns drawn by OUP for OHCS-3 ; no link available; page 45

69 Image of fetal heart deceleration patterns drawn for OHCS-3 by OUP ; no link available; page 45

70 NICE Guideline 2001 Electronic Fetal Monitoring [Link]; page 45

71 Accuracy and limitations of transabdominal fetal echocardiography at 12-15 weeks of gestation in a population at high risk for congenital heart disease. Simpsom JM, BJOG; 2000; 107:1492 PubMed ID: 11192105 [Link]; page 46

72 Lancet. 2000 Jan 8;355(9198):87-92. von Dadelszen P. Fall in mean arterial pressure and fetal growth restriction in pregnancy hypertension: a meta-analysis. [Link]; page 48

73 Lancet. 2002 Feb 23;359(9307):673-4. Wang JX. Surgically obtained sperm, and risk of gestational hypertension and pre-eclampsia. [Link]; page 48

74 Viske BE 2008 NEJM 359 800. Preeclampsia and risk of end-stae renal failure. [Link]; page 48

75 Brain lesions in newborns exposed to high-dose magnesium sulfate during preterm labor. Author: Mittendorf R, Dammann O, Lee KS. Journal: J Perinatol; 2006 Jan 1 ; 26(1):57-63. PubMed ID: 16319938. [Link]; page 48

76 The effect of second-trimester antibiotic therapy on the rate of preterm birth. Author: Morency AM, Bujold E. Journal: J Obstet Gynaecol Can; 2007 Jan ; 29(1):35-44. PubMed ID: 17346476. [Link]; page 50

77 BJOG. 2000 Jul;107(7):877-84. Baud O. The relationships between antenatal management, the cause of delivery and neonatal outcome in a large cohort of very preterm singleton infants. [Link]; page 50

78 N Engl J Med. 1999 Jan 14;340(2):154. Oei SG. Myocardial infarction during nifedipine therapy for preterm labor [Link]; page 50

79 Lancet. 2000 Jan 8;355(9198):87-92. von Dadelszen P. Fall in mean arterial pressure and fetal growth restriction in pregnancy hypertension: a meta-analysis. [Link]; page 52

80 Lancet. 1999 Apr 10;353(9160):1202-4. Schatz M. Asthma and pregnancy. [Link]; page 52

81 E Eichenwald 2008 NEJM 358 1700. Management and outcomes of very low birthweight. [Link]; page 52

82 Br J Obstet Gynaecol. 1999 May;106(5):481-5. Boulvain M. Sweeping of the membranes to prevent post-term pregnancy and to induce labour: a systematic review. Medline abstract, Meta-analysis [Link]; page 54

83 Incidence, treatment and outcome of peripartum sepsis. Author: Kankuri E, Kurki T, Carlson P, Hiilesmaa V. Journal: Acta Obstet Gynecol Scand; 2003 Aug ; 82(8):730-5. PubMed ID: 12848644. [Link]; page 55

84 Acta Obstet Gynecol Scand. 1999 Mar;78(3):186-90. Chan CC. Antepartum hemorrhage of unknown origin--what is its clinical significance? [Link]; page 56

85 Geburtshilfe Frauenheilkd. 1982 Nov;42(11):798-802.The maternal perception of fetal movements during the last trimester of pregnancy Schmidt W [Link]; page 58

86 Towards better births. 2008 Health Care Commission. [Link]; page 58

87 BJOG. 2000 Jul;107(7):939-40. Acute postpartum myocardial infarction after ergometrine administration in a woman with familial hypercholesterolaemia. Mousa HA [Link]; page 58

88 Image of normal labour drawn by OUP for OHCS 1e ; no link available; page 59

89 BJOG. 2000 Feb;107(2):222-7. Ngai SW. Labour characteristics and uterine activity: misoprostol compared with oxytocin in women at term with prelabour rupture of the membranes. [Link]; page 60

90 Reproduced with permission from the Oxford Handbook of Obstetrics and Gynaecology, 2nd Edition ; no link available; page 63

91 J Womens Health Gend Based Med. 1999 Dec;8(10):1257-64. Scott KD. The obstetrical and postpartum benefits of continuous support during childbirth. [Link]; page 65

92 N Engl J Med. 1995 Sep 21;333(12):745-50. Frigoletto FD Jr. A clinical trial of active management of labor. [Link]; page 65

93 Towards better births. 2008 Health Care Commission. [Link]; page 66

94 BJOG. 2000 Oct;107(10):1248-51. Related Articles, Books, LinkOut Subcutaneous versus intracutaneous injections of sterile water for labour analgesia: a comparison of perceived pain during administration.Martensson L, Nyberg K, Wallin G. &: Contemp Rev Obs 12 29 [Link]; page 66

95 RCOG 2005 Greentop Guideline 26 Operative Vaginal Delivery [Link]; page 66

96 2001 Why Mothers Die 1997–9 Annexe C, chapter 2 page 74 RCOG; no link available; page 66

97 Prediction of chorionicity in twin pregnancies at 10-14 weeks of gestation. Carroll SG, BJOG; 2002 Feb ; 109:182. PubMed ID: 11905430 [Link]; page 68

98 Psychological consequences of having triplets: a 4-year follow-up study. Garel M. Fertil Steril; 1997 Jun ; 67(6):1162-5. PubMed ID: 9176462 [Link]; page 69

99 Psychological reactions after multifetal pregnancy reduction: a 2-year follow-up study. Garel M. Hum Reprod; 1997 Mar ; 12(3):617-22. PubMed ID: 9130770 [Link]; page 69

100 Dramatic reduction in triplet and higher order births in England and Wales. Simmons R, BJOG; 2004; 111:856 PubMed ID: 15270936 [Link]; page 69

101 External cephalic version: a safe procedure? A systematic review of version-related risks. Collaris RJ, Acta Obstet Gynecol Scand; 2004 ; 83:511. PubMed ID: 15144330 [Link]; page 70

102 Planned caesarean section versus planned vaginal birth for breech presentation at term: a randomised multicentre trial. Term Breech Trial Collaborative Group. Hannah ME, Lancet; 2000; 356:1375. PubMed ID: 11052579 [Link]; page 70

103 From the Daily Telegraph 17/05/2006. Why I still believe in home births [Link]; page 72

104 he mortality and morbidity associated with umbilical cord prolapse. Author: Murphy DJ, MacKenzie IZ. Journal: Br J Obstet Gynaecol; 1995 Oct ; 102(10):826-30. PubMed ID: 7547741. [Link]; page 72

105 RCOG 2008 Green-top guidelines. Prolapsed cord. [Link]; page 72

106 RCOG 2005 Green-top guidelines. Shoulder dystocia. [Link]; page 72

107 Changing obstetric practices associated with decreasing incidence of meconium aspiration syndrome. Yoder BA, Obstet Gynecol; 2002; 99:731 PubMed ID: 11978280 [Link]; page 73

108 Intrapartum amnioinfusion for meconium-stained amniotic fluid: a systematic review of randomised controlled trials. Author: Xu H, Hofmeyr J, Roy C, Fraser WD. Journal: BJOG; 2007 Apr ; 114(4):383-90. PubMed ID: 17378813. [Link]; page 73

109 Amnioinfusion for the prevention of the meconium aspiration syndrome. Author: Fraser WD, Hofmeyr J, Lede R, Faron G, Alexander S, Goffinet F, Ohlsson A, Goulet C, Turcot-Lemay L, Prendiville W, Marcoux S, Laperrière L, Roy C, Petrou S, Xu HR, Wei B, Amnioinfusion Trial Group . Journal: N Engl J Med; 2005 Sep 1 ; 353(9):909-17. PubMed ID: 16135835. [Link]; page 73

110 Surfactant for meconium aspiration syndrome in full term/near term infants. Author: El Shahed AI, Dargaville P, Ohlsson A, Soll RF. Journal: Cochrane Database Syst Rev; 2007 ; (3):CD002054. PubMed ID: 17636695. [Link]; page 73

111 Towards better births. 2008 Health Care Commission. [Link]; page 73

112 Communication between members of the cardiac arrest team--a postal survey. Author: Pittman J, Turner B, Gabbott DA. Journal: Resuscitation; 2001 May ; 49(2):175-7. PubMed ID: 11382523. [Link]; page 73

113 RCOG 2008 Green-top guidelines. Plolapsed cord. [Link]; page 73

114 BJOG. 2000 Jul;107(7):932-4. Related Articles, Books, LinkOut Outcome of the next labour in women who had a vaginal delivery in their first pregnancy. Mawdsley SD [Link]; page 76

115 Image of brachial plexus injury from OUP image bank. ; no link available; page 77

116 Brachial plexus paresis associated with fetal neck compression from forceps. Author: Gei AF, Smith RA, Hankins GD. Journal: Am J Perinatol; 2003 Aug ; 20(6):289-91. PubMed ID: 14528397 [Link]; page 77

117 Associated factors in 1611 cases of brachial plexus injury. Author: Gilbert WM, Nesbitt TS, Danielsen B. Journal: Obstet Gynecol; 1999 Apr ; 93(4):536-40. PubMed ID: 10214829 [Link]; page 77

118 Obstetrical brachial plexus palsy--etiopathogenesis, risk factors, prevention, prognosis Author: Gosk J, Rutowski R. Journal: Ginekol Pol; 2004 Oct ; 75(10):814-20. PubMed ID: 15587915 [Link]; page 77

119 Effect of operative vaginal delivery on the outcome of permanent brachial plexus injury. Author: Poggi SH, Ghidini A, Allen RH, Pezzullo JC, Rosenbaum TC, Spong CY. Journal: J Reprod Med; 2003 Sep ; 48(9):692-6. PubMed ID: 14562633. [Link]; page 77

120 RCOG Clinical Guideline 37 2004 Thomboprophylaxis [Link]; page 79

121 NICE Clinical Guideline 2004 Caesarean section [Link]; page 79

122 [Prophylaxis and therapy of the acid aspiration syndrome] Author: Ellmauer S. Journal: Anaesthesist; 1987 Nov ; 36(11):599-607. PubMed ID: 3322095. [Link]; page 80

123 RCOG 2005 Good Practice Paper 4 Registration of stillbirths and certification for pregnancy loss before 24 weeks of gestation [Link]; page 83

124 The B-Lynch technique for postpartum haemorrhage: an option for every gynaecologist. Holtsema H, Eur J Obstet Gynecol Reprod Biol; 2004; 115:39 PubMed ID: 15223163 [Link]; page 84

125 M Hall 2004 Ch 4 in Why Mothers Die; Confidential Enquiry into Maternal and Child Health 2000–2 [Link]; page 85

126 Lancet. 1999 Sep 18;354(9183):983-6. Fynes M. Effect of second vaginal delivery on anorectal physiology and faecal continence: a prospective study. [Link]; page 91

127 Image of episeotomy drawn for OHCS-2 by OUP ; no link available; page 93

128 Contraceptive choices for breastfeeding women 2004 Br J Fam Plan and Reprod 30 181 [Link]; page 95

Web-based references relating to the disc signs in footnotes, organised by page number

Antenatal and postnatal mental health: clinical management and service guidance [Link]; page 2

RCOG 2007 Diabetes in pregnancy. Are we providing the best care? [Link]; page 2

RCOG Statement no 5. Alcohol consumption and outcomes of pregnancy [Link]; page 2

RCOG 2007 Diabetes in Pregnancy Are we providing the best care?[Link]; page 3

2008 NICE Clinical Guideline 63 Diabetes in Pregnancy [Link]; page 3

An estimation of intrapartum-related perinatal mortality rates for booked home births in England and Wales between 1994 and 2003. Mori R, BJOG; 2008; 115:554 PubMed ID: 18333936 [Link]; page 5

Saving Mothers’ Lives: Reviewing maternal deaths to make motherhood safer [Link]; page 7

Pregnancy weight gain: still controversial. Author: Abrams B, Altman SL, Pickett KE. Journal: Am J Clin Nutr; 2000 May ; 71(5 Suppl):1233S-41S [Link]; page 7

Discordance in nuchal translucency thickness in the prediction of severe twin-to-twin transfusion syndrome. Kagan KO, Ultrasound Obstet Gynecol; 2007; 29:527 PubMed ID: 17444560 [Link]; page 11

Fetal nuchal translucency thickness. Witters I, Genet Couns; 2007 ; 18:1. PubMed ID: 17515296 [Link]; page 11

Chromosomal abnormality rates at amniocentesis and in live-born infants. Author: Hook EB, Cross PK, Schreinemachers DM. Journal: JAMA; 1983 Apr 15 ; 249(15):2034-8. PubMed ID: 6220164. [Link]; page 12

Maternal age and Down's. [Link]; page 12

American College of Obstetricians and Gynecologists (ACOG). Later Childbearing. ACOG, Washington, DC, 1999. [Link]; page 12

Dose dependency between cigarette consumption and reduced maternal serum PAPP-A levels at 11-13(+6) weeks of gestation. Kagan KO, Prenat Diagn; 2007; 27:849. PubMed ID: 17590888 [Link]; page 12

In vitro fertilization with preimplantation genetic screening. Mastenbroek S, N Engl J Med; 2007; 357:9. PubMed ID: 17611204 [Link]; page 13

p82 in Saving Mothers’ Lives: Reviewing maternal deaths to make motherhood safer 2003-5 [Link]; page 14

page 68 in Saving Mothers’ Lives: Reviewing maternal deaths to make motherhood safer 2003-5 [Link]; page 16

Relapse of major depression during pregnancy in women who maintain or discontinue antidepressant treatment. Cohen L JAMA; 2006 295 499. PubMed ID: 16449615 [Link]; page 21

2007 NICE clinical guideline 45 Antenatal and postnatal mental health [Link]; page 21

Paroxetine and congenital malformations: meta-Analysis and consideration of potential confounding factors. Bar-Oz B, Clin Ther; 2007; 29:918. PubMed ID: 17697910 [Link]; page 21

NICE guideline 2008 Diabetes in pregnancy [Link]; page 24

Propylthiouracil versus methimazole in treatment of Graves' disease during pregnancy. Chattaway JM, Ann Pharmacother; 2007; 41:1018. PubMed ID: 17504839 [Link]; page 25

Unresolved questions in managing hypothyroidism during pregnancy. Glinoer D, BMJ; 2007 ; 335:300. PubMed ID: 17690371 [Link]; page 25

RCOG 2006 Greentop Guideline 43 Obstetric cholestasis [Link]; page 26

Malaria misconceptions. Nosten F, Lancet; 2005; 365 653. PubMed ID: 15721465 [Link]; page 27

Effect of sulfadoxine-pyrimethamine resistance on the efficacy of intermittent preventive therapy for malaria control during pregnancy: a systematic review. ter Kuile FO, van Eijk AM, Filler SJ. JAMA; 2007 Jun 20 ; 297:2603 PubMed ID: 17579229 [Link]; page 27

Asymptomatic bacteriuria and symptomatic urinary tract infections during pregnancy. Macejko AM, Urol Clin North Am; 2007; 34:35 PubMed ID: 17145359 [Link]; page 28

Am J Med Genet. 2001 Jan 15;98(2):168-75. Kozma C. Valproic acid embryopathy: report of two siblings with further expansion of the phenotypic abnormalities and a review of the literature. [Link]; page 29

Pregnancy in rheumatology patients exposed to anti-tumour necrosis factor (TNF)-alpha therapy. Roux CH, Rheumatology (Oxford); 2007; 46:695 PubMed ID: 17158212 [Link]; page 30

RCOG 2007 Greentop Guideline 28 Thromboembolic disease in pregnancy and the puerperium: Acute management. [Link]; page 32

Laparoscopic appendectomy during pregnancy: between personal experiences and scientific evidence. Moreno-Sanz C, J Am Coll Surg; 2007; 205:37. PubMed ID: 17617330 [Link]; page 38

Fetal electrocardiogram (ECG) for fetal monitoring during labour. Author: Neilson JP. Journal: Cochrane Database Syst Rev; 2006 ; 3():CD000116. PubMed ID: 16855950 [Link]; page 44

Fetal pulse oximetry and cesarean delivery. Bloom SL, National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network . N Engl J Med; 2006 Nov 23 ; 355(21):2195-202. PubMed ID: 17124017 [Link]; page 44

BJOG. 2000 Dec;107(12):1492-7. Simpsom JM. Accuracy and limitations of transabdominal fetal echocardiography at 12-15 weeks of gestation in a population at high risk for congenital heart disease. [Link]; page 47

Antibiotics in preterm labour--the Oracle speaks [Link]; page 50

Childhood outcomes after prescription of antibiotics to pregnant women with spontaneous preterm labour: 7-year follow-up of the ORACLE II trial [Link]; page 50

Cerebral palsy among very preterm children in relation to gestational age and neonatal ultrasound abnormalities: the EPIPAGE cohort study. Ancel PY, EPIPAGE Study Group . Pediatrics; 2006; 117:828 PubMed ID: 16510664 [Link]; page 51

Repeat doses of prenatal corticosteroids for women at risk of preterm birth for preventing neonatal respiratory disease. Crowther C, Database Syst Rev; 2007 CD003935. PubMed ID: 17636741 [Link]; page 51

Critical care decisions in fetal and neonatal medicine; ethical issues [Link]; page 51

Perinatal Mortality 2005 [Link]; page 51

Induction of labour for improving birth outcomes for women at or beyond term. Gülmezoglu AM, Cochrane Database Syst Rev; 2006 ; 56 :CD004945. PubMed ID: 17054226 [Link]; page 54

CG62 Antenatal Care [Link]; page 54

CEMACH publication Perinatal Mortality 2005 [Link]; page 54

p97 in Saving Mothers’ Lives: Reviewing maternal deaths to make motherhood safer 2003-5 [Link]; page 55

Association of caesarean delivery for first birth with placenta praevia and placental abruption in second pregnancy. Yang Q, BJOG; 2007; 114:609. PubMed ID: 17355267 [Link]; page 56

Thrombophilia in pregnancy: a systematic review. Robertson L, The Thrombosis: Risk and Economic Assessment of Thrombophilia Screening (TREATS) Study . Br J Haematol; 2006; 132:171. PubMed ID: 16398652 [Link]; page 56

Br J Obstet Gynaecol. 1984 Oct;91(10):1014-8. Singhi S. Intrapartum infusion of aqueous glucose solution, transplacental hyponatraemia and risk of neonatal jaundice. [Link]; page 58

East Afr Med J. 1991 Feb;68(2):88-92. Omigbodun AO. Effects of using either saline or glucose as a vehicle for infusion in labour. [Link]; page 58

Eur J Obstet Gynecol Reprod Biol. 1995 Apr;59(2):149-51. Stratton JF. Hyponatraemia and non-electrolyte solutions in labouring primigravida. [Link]; page 58

Eur J Obstet Gynecol Reprod Biol. 1996 Sep;68(1-2):47-8. Higgins J. Maternal and neonatal hyponatraemia: a comparison of Hartmanns solution with 5% dextrose for the delivery of oxytocin in labour. [Link]; page 58

Saving Mothers Lives: Reviewing maternal deaths to make motherhood safer 2003-5 [Link]; page 58

Planned early birth versus expectant management (waiting) for prelabour rupture of membranes at term (37 weeks or more). Dare MR, Cochrane Database Syst Rev; 2006 ; 20:CD005302. PubMed ID: 16437525 [Link]; page 60

Oral misoprostol administration for labor induction. Weeks A, Clin Obstet Gynecol; 2006; 49:658. PubMed ID: 16885670 [Link]; page 62

Combined spinal-epidural versus epidural analgesia in labour. Simmons S, Cochrane Database Syst Rev; 2007 ; 197:CD003401. PubMed ID: 17636721 [Link]; page 67

Managing twins discordant for fetal anomaly. Author: Rustico MA, Baietti MG, Coviello D, Orlandi E, Nicolini U. Journal: Prenat Diagn; 2005 Sep ; 25(9):766-71. PubMed ID: 16170860. [Link]; page 68

RCOG 2007 Scientific Advisory paper 8 Perinatal risks associated with IVF [Link]; page 69

Greentop Guideline 20(a) External cephalic version [Link]; page 70

External cephalic version for breech presentation with or without spinal analgesia in nulliparous women at term: a randomized controlled trial. Weiniger CF, Obstet Gynecol; 2007 110:1343 PubMed ID: 18055730 [Link]; page 70

RCOG 2006 Greentop Guideline 20(b) The management of Breech presentation [Link]; page 70

Five years to the term breech trial: the rise and fall of a randomized controlled trial. Author: Glezerman M. Journal: Am J Obstet Gynecol; 2006; 194:20. PubMed ID: 16389006 [Link]; page 70

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