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Synthetic Peptides
A User's Guide

Second Edition

Edited by Gregory Grant

Price: £54.00 (paper)
ISBN-13: 978-0-19-513261-8
Publication date: 30 May 2002
400 pages, 64 line illus, 6-1/8 x 9-1/4 mm
Series: Advances in Molecular Biology
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Description
  • Provides useful information for both novices in the field as well as seasoned practitioners
  • Each chapter contains practical advice for setting up and performing protocols
  • Comprehensive coverage of peptide synthesis including not only the chemistry, but design, synthesis, analysis, and application of the product
The first synthetic peptides were produced a century ago. In the ensuing period, they have developed as valuable research tools that are readily available to all researchers. However, since most researchers do not make their own peptides, they are oftenunfamiliar with not only the synthetic chemistry but also with important and useful aspects of design, analysis, handling and applications. This volume is the second edition of a volume that was first published 10 years ago. It is written by experts in the field who provide detailed descriptions as well as practical advice for producing and using synthetic peptides. The various chapters cover peptide design considerations, the synthetic chemistry, the evaluation of the synthetic product, and the modern applications of synthetic peptides. This includes the basic principles of peptide structure, analysis and chain assembly as well as the latest in selective disulfide bond formation, new strategies for the production of large peptides, and sequencing peptides by mass spectrometry. This book was designed with the intent of providing useful information both for the novices to the field as well as more seasoned practitioners. Its contents will help prevent problems commonly encountered and allow scientists to optimize their use of synthetic peptides.

Contents
Contributors
1. Synthetic Peptides: Beginning the Twenty-first Century , Gregory A. Grant
2. Peptide Design Considerations , Michael L. Moore & Gregory A. Grant
3. Principles and Practice of Solid-Phase Peptide Synthesis , Gregg B. Fields, Janelle L. Lauer-Fields, Rong-qiang Liu, & George Barany
4. Evaluation of the Synthetic Product , Gregory A. Grant
5. Applications of Synthetic Peptides , Victor J. Hruby & Terry O. Matsunaga
Index

Authors, editors, and contributors


Edited by Gregory Grant, Professor of Biochemistry in Medicine and of Molecular Biology and Pharmacology, Washington University School of Medicine, St.Louis


Links to web resources and related information
More in the same subject area:
Polymer chemistry

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