| Description | | - Written by an international group of experts in the field. It provides a survey of the literature, emphasising the most useful techniques and reagents.
- Each chapter contains step-by-step protocols, essential background information and key citations in the literature.
| | Organophosphorus Chemistry: A Practical Approach in Chemistry provides a practical introduction to the field by mixing a brief review of the subject area with key experimental details and sample procedures. Phosphorus is an element that has been central to the development of our modern way of life. Its chemistry plays a key role in the development of such important areas as pharmaceuticals,
agrochemicals, modern materials and molecular biology. Much of this work requires a sound understanding of the organic chemistry of phosphorus and this volume is designed to instruct the reader in the essential methodology used. Topics covered include phosphines, applications of phosphorus (III) and (V) compounds as reagents in synthesis, the chemistry of phosphorus ylides, applications of the
Wittig reaction in the synthesis of heterocyclic and carbocyclic compounds, preparation of Iminophosphoranes and their synthetic applications in the aza-Wittig reaction, phospho-transfer processes leading to [P-C] bond formation, low valent phosphorus compounds and phosphorus methods in oligonucleotide chemistry. It is intended not only for the specialist in organophosphorus chemistry, but also
for the organic chemist with little experience in the field who wishes to add phophorus-based techniques to his or her ensemble of synthetic methods. |
Readership: Chemistry academics, postgraduates, industrial and professional researchers. Will also appeal to final year chemistry undergraduates.
| Contents |
1.
Introduction to "Organophosphorus Chemistry"
,
Dr P.J. Murphy
2.
The synthesis and applications of Phosphines
,
Professor Jonathan Williams and Matthew Clarke
3.
Applications of phosphorus (III) and (V) compounds as reagents in synthesis
,
Dr R. Alan Aitken and Nazira Karodia
4.
The Wittig and related Reactions
,
Dr Andrew Abell and Dr Michael Edmonds
5.
Applications of the Wittig reaction in the synthesis of heterocyclic and carbocyclic compounds
,
Dr Ranier Schobert
6.
Preparation and reactions of Iminophosphoranes and their synthetic applications in the aza-Wittig reaction
,
Dr I O'Neil and Dr J.M. Southern
7.
Phospho-Transfer processes leading to (P-C) bond formation
,
Dr Matthew D. Fletcher
8.
Low-coordinated phosphorus compounds
,
Dr Sven Asmus, Dr Uwe Bergstrasser, Dr Heinrich Heydt, Dr Marion Schmitz and Professor Manfred Regitz
9.
Phosphorus methods in nucleotide chemistry
,
Dr David M. Williams and Dr Vicki H. Harris
|
| Authors, editors,
and contributors |
Patrick J. Murphy, Department of Chemistry, University of Wales, Bangor
| | Contributors:Dr Andrew Abell, Dr R. Alan Aitken, Dr. Sven Asmus, Dr. Uwe Bergstrasser, Dr. Matthew Clarke, Dr. Michael Edmonds, Dr. Vicki Harris, Dr. Heinrich Heydt, Dr. David M. Williams, Dr. Patrick J. Murphy, Dr. I O'Neil, Professor Manfred Regitz, Dr. Marion Schmitz, Professor Rainer Schobert, Dr. David M Williams, Professor Jonathan Williams |
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