Polymorphism in Molecular Crystals
Joel Bernstein
Price: £99.00 (hardback)
ISBN-13: 978-0-19-850605-8
Publication date: 16 May 2002
424 pages, 4 color plates, 170 line illus., 234x156 mm
Series: International Union of Crystallography Monographs on Crystallography number 14
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| Reviews |
| - '... clear, vigorous, well-written and very readable ... There seems to be nothing relevant that Bernstein has not included; his scholarship and command and study of the vast literature are remarkable ... an excellent work.' - Current Engineering Practice
- 'Joel Bernstein's book represents the single most important source for the development of critical understanding of polymorphism and its commercial and industrial importance and might well play a decisive role in categorizing and reorganizing problems and endeavours on polymorphism-related research.' - Current Engineering Practice
- 'Prof. Joel Bernstein displays an impressive grasp of the subject of polymorphism, making possible a lot of information more accessible to the interesed reader.' - Current Engineering Practice
- '... an excellent resource book and a very good read ... can be recommended strongly both for content and interest.' - Robert Gould, Crystallographic Newsletter
- '... a delight to review this eagerly awaited tome ... In the end, the proof of the pudding is in the eating, and in my opinion, Bernstein has served us a nutritional feast here. Enjoy!' - Roger J. Davey, Cryst. Growth Des.
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| Description | | - First comprehensive coverage of this subject in one volume
- Includes physical principles, control, experimental and computational aspects, and structure-property relations
- Numerous diagrams illustrate similarities and differences in structure and properties
- Many examples from the fields of pharmaceuticals, pigments, explosives are included throughout
- Importance in recent patent litigations
| | Polymorphism - the multiplicity of structures or forms - is a term that is used in many disciplines. In chemistry it refers to the existence of more than one crystal structure for a particular chemical substance. The properties of a substance are determined by its composition and by its structure. In the last two decades, there has been a sharp rise in the interest in polymorphic systems, as an
intrinsically interesting phenomenon and as an increasingly important component in the development and marketing of a variety of materials based on organic molecules (e.g. pharmaceuticals, dyes and pigments, explosives, etc.). This book summarizes and brings up to date the current knowledge and understanding of polymorphism of molecular crystals, and concentrates it in one comprehensive source.
The book will be an invaluable reference for students, researchers, and professionals in the field. |
Readership: Graduate students, researchers, and professionals in crystallography, chemistry, materials science, and pharmacology.
| Contents |
Preface
1.
Introduction and historical background
2.
Fundamentals
3.
Controlling the polymorphic form obtained
4.
Analytical techniques for studying and charaterizing polymorphs
5.
Conformational polymorphism - intra- and intermolecular energetics
6.
Polymorphism and structure-property relations
7.
Polymorphism of pharmaceuticals
8.
Polymorphism of dyes and pigments
9.
Polymorphism of high energy materials
10.
Polymorphism and patents
References
Index
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| Authors, editors,
and contributors |
Joel Bernstein, Department of Chemistry, Ben-Gurion, University of the Negev, Beer Sheva, Israel
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