The Weak Hydrogen Bond
In Structural Chemistry and Biology
Gautam R. Desiraju and Thomas Steiner
Price: £52.00 (paper)
ISBN-13: 978-0-19-850970-7
Publication date: 31 May 2001
526 pages, 535 line illus, 234x156 mm
Series: International Union of Crystallography Monographs on Crystallography number 9
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| Reviews |
| Review(s) from previous edition:
- '"For crystallographers interested in future advances in the study of hydrogen bonding and their implications for crystal engineering and structural biology, this is a must-read book " Acta Crystallographica' -
- '"It is a real pleasure to read the book" Crystallography News' -
- '"This book is an important monograph for those working on the related structural chemistry of the weak hydrogen bond" Molecules' -
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| Description | | - Comprehensive approach to a modern topic
- Extensively referenced and illustrated
| The weak or non-conventional hydrogen bond has been subject of intense scrutiny over recent years in several fields, in particular in structural chemistry, structural biology, and also in the pharmaceutical sciences. There is today a large body of experimental and theoretical evidence confirming that hydrogen bonds like C-H...O, N-H...pi, C-H...pi and even bonds like O-H...metal play
distinctive roles in molecular recognition, guiding molecular association, and in determining molecular and supramolecular architectures. The relevant compound classes include organometallic complexes, organic and bio-organic systems, and also DNA and proteins. The book provides a comprehensive assessment of this interaction type, and is of interest to all those interested in structural and
supramolecular science, including fields as crystal engineering and drug design.
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Readership: Researchers in structural chemistry and biology. Crystallographers interested in intermolecular interactions.
| Contents |
Acknowledgements
1.
Introduction
2.
Archetypes of the weak hydrogen bond - C--H...O and C--H...N interactions in organic and organometallic systems
3.
Other weak and non-conventional hydrogen bonds
4.
The weak hydrogen bond in supramolecular chemistry
5.
The weak hydrogen bond in biological structures
6.
Conclusions
Appendix--Some bibliographic statistics
References
Index
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| Authors, editors,
and contributors |
Gautam R. Desiraju, Professor at the School of Chemistry, University of Hyderabad and
Thomas Steiner, Lecturer at the Institut für Kristallographie, Freie Universität Berlin
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