| Description | | - Establishes an original sequence of topics in a clear, fresh and original way, setting it apart from the other texts in the subject
- Useful case studies support student learning
- A great introduction to the contemporary study of proteins
- Logical, fluid and unambigious text written by a well-respected author
- Exercises, Problems and 'Weblems' (web-based problems) consolidate and extend students' understanding of the subject
- Comments in the margin help students appreciate the flow of the presentation, acting as links between sections and bolstering their confidence in the subject matter
- Online Resource Centre - downloadable figures, a Web Link library and animated illustrations will be available at www.oup.com/uk/booksites/biosciences/
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Proteins are essential to life, having a vital role in all living organisms. They are the ultimate micro machines: some are building blocks, joining with other substances to make the cells from which we are all formed. Some are catalysts, speeding up essential biochemical reactions to keep our cells alive. Yet others help cells to communicate, to move, and to build up the complex mix of tissues
that make up our bodies.
Introduction to Protein Science
provides a broad ranging introduction to the contemporary study of proteins suitable for students on biosciences degrees internationally. Starting by describing the structure of proteins and how these structures can be studied, the book goes on to illustrate the wide range of functions that proteins have, showing how the shape of
a protein is intimately linked to the function that it has. The book then describes how new experimental and computational techniques are helping us to predict a protein s structure and function, and how this is paving the way for us to design new proteins with specific characteristics, with exciting implications in areas such as drug design.
Written by Arthur Lesk, the author of the highly
successful Introduction to Bioinformatics, this book offers the same clear, student friendly approach to an equally important area of bioscience. Recent advances in genomics and proteomics have paved the way for an explosion of interest in protein structure and function. This book captures the current state of excitement in a way that all biosciences students will find appealing.
Online
Resource Centre:
- Downloadable figures
- A Web link library
- Animated illustrations (pictures of complicated structures are much more effective if presented as animations; this
will take the form of a computer-readable supplement to the book).
All these will be available on the Online Resource Centre at www.oup.com/uk/booksites/biosciences/
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Readership: The target level for this text is aimed at second and third year undergraduate students, in particular those students on biosciences degree courses internationally.
| Contents |
Preface
1. The Ribosome - the fulcrum of genomics
2. The Genomics of Proteins
3. Protein Structure
The building blocks
Spatial aspects of protein structure
Proteins in the cell, in solution, in crystals
Structure determination at and near atomic resolution
4. Protein Function
5. Protein Architecture and Evolution
Hierarchy of structure description
Evolution of protein structures and functions
Modelling and prediction of protein structure and function
6. Protein Engineering, Folding and Design
7. Proteins with Partners
8. Proteins in Membranes
9. Proteins in Disease
Epilogue: The future of protein science
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| Authors, editors,
and contributors |
Arthur M. Lesk, Senior Research Associate, Department of Haematology, University of Cambridge
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The specification in this catalogue, including without
limitation price, format, extent, number of illustrations,
and month of publication, was as accurate as
possible at the time the catalogue was compiled.
Occasionally, due to the nature of some contractual restrictions, we
are unable to ship a specific product to a particular territory.
Jacket images are provisional and liable to change before publication.
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